The Science Behind Dellawell
Black seed oil is one of the most clinically studied natural compounds in the world — with 80+ published trials examining its effects on cardiovascular and metabolic health. Below are the key studies behind Dellawell's formulation, summarized in plain English, each linked to its original source so you can read the science yourself.
Blood Pressure Research
What the clinical evidence shows about black seed oil and cardiovascular health.
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Systematic review & meta-analysis: Nigella sativa and blood pressure
Researchers pooled 12 randomized clinical trials to measure the overall effect of black seed on blood pressure — and compared the oil form directly against powder.
Key finding: Black seed oil significantly lowered both systolic and diastolic blood pressure — and the oil form was significantly more effective than powder. The analysis also found reductions in fasting blood sugar, total cholesterol, and LDL.
View study →Pooled analysis of randomized controlled trials on blood pressure
A separate meta-analysis of 11 randomized controlled trials measured average blood pressure changes across 860 participants supplementing with Nigella sativa.
Key finding: Average systolic blood pressure dropped from approximately 133 to 125 mmHg and diastolic from 83 to 78 mmHg after roughly 8 weeks of use.
View study →Clinical trial on thymoquinone-standardized black seed oil
This trial used black seed oil standardized for thymoquinone content — the same standardization approach Dellawell uses — to measure effects on blood pressure and heart rate in volunteers.
Key finding: Volunteers experienced an 11.2% decrease in systolic and a 12.2% decrease in diastolic blood pressure over the 6-week treatment period — using oil standardized to just 3% TQ. Dellawell is standardized to 5%.
View study →Review of Nigella sativa's effects on cardiovascular risk factors
A broad review of the published evidence on black seed and heart health markers, including blood pressure, cholesterol, and inflammatory markers.
Key finding: Consistent improvements across multiple cardiovascular risk markers, with no significant adverse effects reported at studied doses.
View study →Thymoquinone's antioxidant & anti-inflammatory mechanisms
This research examines how thymoquinone works at the cellular level — reducing the oxidative stress and inflammation that degrade vascular function over time.
Key finding: Thymoquinone demonstrated potent antioxidant and anti-inflammatory activity — the mechanism behind its cardiovascular and metabolic benefits.
View study →Blood Sugar Research
What the clinical evidence shows about black seed oil and metabolic health.
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Systematic review: Nigella sativa in type 2 diabetes
Researchers reviewed 7 clinical trials on black seed supplementation in people with type 2 diabetes, measuring every major blood sugar marker.
Key finding: Significant improvements in fasting blood glucose, post-meal glucose, HbA1c, and insulin resistance. The authors concluded black seed could serve as a beneficial adjuvant to oral antidiabetic drugs.
View study →Dose-response trial on glycemic control
This landmark trial tested black seed at multiple doses in patients with type 2 diabetes over 12 weeks, tracking HbA1c — the gold-standard marker of long-term blood sugar control.
Key finding: At 2g/day, HbA1c dropped from 9.09% to 7.57% in just 12 weeks — alongside significant reductions in fasting and post-meal glucose. 2g/day is exactly Dellawell's recommended daily serving.
View study →One-year study on sustained metabolic effects
One of the longest-running trials on black seed, following patients with type 2 diabetes for a full year to answer the biggest question: do the effects last?
Key finding: Fasting blood glucose, HbA1c, and insulin resistance showed sustained improvement at 3, 6, 9, and 12 months. The benefits didn't wear off — they compounded with continued use.
View study →Clinical evaluation of black seed on blood glucose regulation
A controlled clinical evaluation of black seed supplementation and its effect on key glycemic and metabolic markers.
Key finding: Meaningful improvements in blood glucose regulation, supporting the pattern seen across the wider body of trials.
View study →Trial on Nigella sativa and metabolic parameters
This clinical study measured black seed's effects across multiple metabolic parameters, including glucose and lipid markers.
Key finding: Improvements across glucose and lipid profiles, reinforcing black seed's dual cardiovascular-metabolic benefit.
View study →Recent clinical evidence on Nigella sativa
One of the most recent additions to the research body, continuing to build the evidence base for black seed's metabolic and cardiovascular effects.
Key finding: The newest research continues to confirm what earlier trials found — meaningful, measurable effects with an excellent safety profile.
View study →The compound behind these studies is thymoquinone.
Dellawell delivers 1000mg of cold-pressed Ethiopian black seed oil at 5% verified thymoquinone per serving.
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